Join thousands of students who trust us to help them ace their exams!Watch the first video
Multiple Choice
The arrival of an action potential at the synaptic knob results in which of the following?
A
Opening of voltage-gated sodium channels in the postsynaptic membrane
B
Inhibition of calcium ion influx into the synaptic knob
C
Reuptake of neurotransmitters into the presynaptic neuron
D
Release of neurotransmitters into the synaptic cleft
Verified step by step guidance
1
Understand the structure and function of a synapse: A synapse is the junction between two neurons where communication occurs. The presynaptic neuron contains the synaptic knob, which is responsible for releasing neurotransmitters into the synaptic cleft.
Recognize the role of an action potential: An action potential is an electrical signal that travels along the axon of a neuron. When it reaches the synaptic knob, it triggers specific processes that lead to neurotransmitter release.
Identify the role of calcium ions: The arrival of the action potential at the synaptic knob causes voltage-gated calcium channels to open. Calcium ions (Ca²⁺) flow into the synaptic knob due to the concentration gradient.
Explain the effect of calcium ion influx: The influx of calcium ions into the synaptic knob initiates the fusion of synaptic vesicles (containing neurotransmitters) with the presynaptic membrane. This process is called exocytosis.
Conclude with neurotransmitter release: Once the synaptic vesicles fuse with the membrane, neurotransmitters are released into the synaptic cleft, where they can bind to receptors on the postsynaptic membrane to propagate the signal.