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Multiple Choice
How do retrotransposons differ from other transposons in their mechanism of transposition?
A
Retrotransposons require a protein coat for transposition.
B
Retrotransposons are unable to transpose within the same cell.
C
Retrotransposons directly insert DNA into the genome without an RNA intermediate.
D
Retrotransposons use an RNA intermediate to transpose.
Verified step by step guidance
1
Understand the basic concept of transposons: Transposons, also known as 'jumping genes,' are DNA sequences that can change their position within the genome. They are categorized into two main types: DNA transposons and retrotransposons.
Differentiate between DNA transposons and retrotransposons: DNA transposons move directly as DNA, while retrotransposons move through an RNA intermediate. This is a key distinction in their mechanisms of transposition.
Explore the mechanism of retrotransposons: Retrotransposons are first transcribed into RNA. This RNA is then reverse-transcribed back into DNA by the enzyme reverse transcriptase. The newly synthesized DNA is then inserted into a new location in the genome.
Clarify the role of reverse transcriptase: Reverse transcriptase is crucial for retrotransposons as it converts the RNA intermediate back into DNA, allowing the transposition process to occur.
Summarize the unique feature of retrotransposons: Unlike DNA transposons, retrotransposons require an RNA intermediate for their transposition, which involves transcription and reverse transcription processes.