Understand the concept of an action potential: An action potential is a rapid electrical signal that travels along the membrane of a neuron. It involves changes in the membrane potential due to the movement of ions across the membrane.
Step 1: Resting potential - The neuron starts at its resting potential, typically around -70 mV. During this phase, the inside of the neuron is more negative compared to the outside, maintained by the sodium-potassium pump and leak channels.
Step 2: Depolarization - A stimulus causes voltage-gated sodium channels to open, allowing Na⁺ ions to rush into the cell. This influx of positive ions makes the inside of the neuron less negative, and the membrane potential rises toward a positive value.
Step 3: Repolarization - Once the membrane potential reaches its peak (around +30 mV), voltage-gated sodium channels close and voltage-gated potassium channels open. K⁺ ions flow out of the cell, restoring the negative membrane potential.
Step 4: Hyperpolarization - The outflow of K⁺ ions can temporarily make the membrane potential more negative than the resting potential. This phase is followed by the return to the resting potential as the sodium-potassium pump re-establishes the original ion distribution.