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Multiple Choice
What controls the progression and regulation of the cell cycle?
A
Ribosomes and endoplasmic reticulum
B
Golgi apparatus and lysosomes
C
Mitochondria and chloroplasts
D
Cyclins and cyclin-dependent kinases (CDKs)
Verified step by step guidance
1
Understand the cell cycle: The cell cycle is a series of phases that cells go through to grow and divide. It includes interphase (G1, S, G2 phases) and mitotic phase (M phase).
Identify the key regulators: Cyclins and cyclin-dependent kinases (CDKs) are the primary molecules that regulate the progression of the cell cycle. Cyclins are proteins whose levels fluctuate throughout the cell cycle, while CDKs are enzymes that, when activated by cyclins, can phosphorylate other proteins to advance the cell cycle.
Explore the role of cyclins: Cyclins bind to CDKs, activating them. Different cyclins are present at different stages of the cell cycle, ensuring that the cycle progresses in a controlled manner.
Examine the function of CDKs: CDKs, once activated by cyclins, phosphorylate target proteins that are crucial for the progression of the cell cycle. This phosphorylation can lead to changes in protein activity, interactions, or localization, driving the cell cycle forward.
Consider checkpoints: The cell cycle is regulated by checkpoints, which are controlled by cyclins and CDKs. These checkpoints ensure that the cell only progresses to the next stage if conditions are favorable, preventing errors such as DNA damage from being passed on.