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Multiple Choice
Which of the following is an example of necrosis rather than apoptosis?
A
Programmed cell death during embryonic development
B
Cell death triggered by activation of caspases
C
Elimination of self-reactive lymphocytes in the thymus
D
Cell death caused by acute physical injury, such as a burn
Verified step by step guidance
1
Understand the difference between necrosis and apoptosis: Necrosis is a form of cell death caused by external factors such as injury, infection, or toxins, and it often leads to inflammation. Apoptosis, on the other hand, is a programmed and controlled process of cell death that occurs naturally during development or to maintain homeostasis.
Review the examples provided in the question: Programmed cell death during embryonic development, cell death triggered by activation of caspases, and elimination of self-reactive lymphocytes in the thymus are all examples of apoptosis, as they involve regulated processes within the cell.
Focus on the last option: Cell death caused by acute physical injury, such as a burn. This is an example of necrosis because it is caused by external physical damage rather than an internally regulated process.
Recognize the key characteristics of necrosis: Necrosis often results in uncontrolled cell death, leakage of cellular contents, and inflammation in the surrounding tissue, which aligns with the description of cell death due to acute physical injury.
Conclude that the correct answer is the option describing cell death caused by acute physical injury, as it matches the definition and characteristics of necrosis.