Multiple Choice
What occurs in the reaction called phosphorylation?
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8. Respiration
Types of Phosphorylation
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Which of the following is an example of autophosphorylation?
A
Activation of receptor tyrosine kinases
B
Phosphorylation of glucose in glycolysis
C
Phosphorylation of proteins by protein kinase A
D
Phosphorylation of ADP to ATP
Verified step by step guidance1
Understand the concept of autophosphorylation: Autophosphorylation is a process where a kinase enzyme adds a phosphate group to itself. This is a key mechanism in signal transduction pathways, particularly in the activation of certain receptors.
Identify the role of receptor tyrosine kinases: Receptor tyrosine kinases (RTKs) are a class of enzymes that, upon binding to a ligand, undergo autophosphorylation. This means they phosphorylate their own tyrosine residues, which is crucial for their activation and subsequent signaling.
Differentiate between the options: Analyze each option to determine if it involves a kinase phosphorylating itself. The activation of receptor tyrosine kinases involves autophosphorylation, whereas the other options involve phosphorylation of different molecules.
Consider the phosphorylation of glucose in glycolysis: This process involves the enzyme hexokinase or glucokinase adding a phosphate group to glucose, not to itself, thus it is not autophosphorylation.
Evaluate the phosphorylation by protein kinase A and ADP to ATP: Protein kinase A phosphorylates other proteins, not itself, and the conversion of ADP to ATP involves the addition of a phosphate group to ADP, not a kinase phosphorylating itself.
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