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Multiple Choice
Which of the following are post-transcriptional modifications of mRNA?
A
5' capping
B
Protein folding
C
DNA replication
D
Polyadenylation
Verified step by step guidance
1
Understand that post-transcriptional modifications are changes made to mRNA after it is transcribed from DNA but before it is translated into protein.
Identify the common post-transcriptional modifications: 5' capping, polyadenylation, and splicing.
5' capping involves the addition of a modified guanine nucleotide to the 5' end of the mRNA, which helps protect the mRNA from degradation and assists in ribosome binding during translation.
Polyadenylation is the addition of a poly-A tail to the 3' end of the mRNA, which also helps stabilize the mRNA and regulate its translation.
Recognize that protein folding and DNA replication are not post-transcriptional modifications of mRNA. Protein folding occurs after translation, and DNA replication is a separate process related to DNA synthesis.