Multiple Choice
What is paracrine signaling?
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10. Cell Signaling
Introduction to Cell Signaling
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What is the primary function of receptor tyrosine kinases in cell signaling?
A
To bind to steroid hormones and initiate transcription
B
To dephosphorylate serine residues on target proteins
C
To transport ions across the cell membrane
D
To phosphorylate tyrosine residues on target proteins
Verified step by step guidance1
Receptor tyrosine kinases (RTKs) are a type of cell surface receptor that play a crucial role in cell signaling.
The primary function of RTKs is to phosphorylate tyrosine residues on target proteins, which is a key step in signal transduction.
When a ligand binds to the extracellular domain of an RTK, it causes the receptor to dimerize, activating its kinase activity.
The activated RTK then transfers a phosphate group from ATP to specific tyrosine residues on itself or other proteins, using its intrinsic kinase activity.
This phosphorylation event creates docking sites for downstream signaling molecules, leading to a cascade of cellular responses.
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