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Multiple Choice
Which of the following hormones has intracellular receptors?
A
Cortisol
B
Glucagon
C
Insulin
D
Epinephrine
Verified step by step guidance
1
Step 1: Understand the concept of intracellular receptors. Intracellular receptors are located inside the cell, typically in the cytoplasm or nucleus, and they bind to signaling molecules that can pass through the cell membrane, such as lipid-soluble hormones.
Step 2: Review the properties of the hormones listed in the question. Determine whether each hormone is lipid-soluble or water-soluble. Lipid-soluble hormones can diffuse through the cell membrane and bind to intracellular receptors, while water-soluble hormones bind to receptors on the cell surface.
Step 3: Analyze the hormone cortisol. Cortisol is a steroid hormone derived from cholesterol, making it lipid-soluble. It can pass through the cell membrane and bind to intracellular receptors in the cytoplasm or nucleus.
Step 4: Examine the other hormones: glucagon, insulin, and epinephrine. These are water-soluble hormones that cannot pass through the cell membrane. Instead, they bind to extracellular receptors on the cell surface, triggering signaling pathways inside the cell.
Step 5: Conclude that cortisol is the hormone with intracellular receptors because it is lipid-soluble and capable of crossing the cell membrane to interact with receptors inside the cell.