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Multiple Choice
How is it possible that as many as 9 million mutations can arise each day in the population of E. coli inhabiting one human?
A
E. coli have a very high mutation rate.
B
The interior of the human colon is particularly mutagenic.
C
Transformation is occurring.
D
Conjugation is occurring.
E
A large population size and a rapid reproduction rate combine to produce many mutations without a particularly high mutation rate.
Verified step by step guidance
1
Understand the context: E. coli is a type of bacteria that resides in the human gut. It reproduces rapidly, which is a key factor in the occurrence of mutations.
Consider the reproduction rate: E. coli can divide approximately every 20 minutes under optimal conditions. This rapid reproduction rate means that a single bacterium can produce a large number of offspring in a short period.
Calculate the population size: Given the rapid reproduction rate, the population of E. coli in the human gut can reach billions. A large population size increases the likelihood of mutations occurring.
Understand mutation occurrence: Mutations are random changes in the DNA sequence. Even with a low mutation rate per cell division, the sheer number of divisions in a large population results in a significant number of mutations.
Combine factors: The combination of a large population size and rapid reproduction rate leads to the emergence of millions of mutations daily, without the need for a particularly high mutation rate per individual bacterium.