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Multiple Choice
Which of the following hypotheses is best supported by observing cancer cells in a culture?
A
The cancer cells produce molecules that inhibit the growth factors required for cell division.
B
The cancer cells exhibit anchorage dependence.
C
The cancer cells spend the majority of their time in the G0 phase.
D
All of the listed responses are correct.
E
The cancer cells do not exhibit density-dependent inhibition.
Verified step by step guidance
1
Understand the concept of cancer cells: Cancer cells are characterized by uncontrolled growth and division, which is a key aspect to consider when evaluating hypotheses about their behavior.
Review the concept of density-dependent inhibition: Normal cells stop dividing when they become crowded, a phenomenon known as density-dependent inhibition. Cancer cells often lack this property, allowing them to continue dividing even when densely packed.
Evaluate the hypothesis regarding density-dependent inhibition: The hypothesis stating that cancer cells do not exhibit density-dependent inhibition aligns with the typical behavior of cancer cells, as they continue to proliferate despite high cell density.
Consider the other hypotheses: Cancer cells typically do not produce molecules that inhibit growth factors; they often bypass normal regulatory mechanisms. Anchorage dependence is a property of normal cells, not cancer cells, and cancer cells do not spend most of their time in the G0 phase, as they are actively dividing.
Conclude which hypothesis is best supported: Based on the characteristics of cancer cells, the hypothesis that they do not exhibit density-dependent inhibition is best supported by observations in a culture.