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Multiple Choice
Which of the following correctly represents the sequence of events that occurs at a chemical synapse?
A
The postsynaptic neuron releases neurotransmitter, which binds to receptors on the presynaptic neuron, causing depolarization.
B
Ca^{2+} leaves the presynaptic neuron, neurotransmitter is degraded in the synaptic cleft, and an action potential is generated in the presynaptic neuron.
C
An action potential arrives at the presynaptic terminal, causing Ca^{2+} influx, neurotransmitter release, binding to postsynaptic receptors, and initiation of a postsynaptic potential.
D
Neurotransmitter is released from the postsynaptic neuron, travels to the presynaptic neuron, and triggers an action potential.
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Verified step by step guidance
1
Understand the concept of a chemical synapse: A chemical synapse is a junction between two neurons where the transmission of signals occurs via neurotransmitters. The presynaptic neuron releases neurotransmitters, which bind to receptors on the postsynaptic neuron, leading to signal propagation.
Step 1: Recognize the sequence of events at a chemical synapse. The process begins when an action potential arrives at the presynaptic terminal, causing voltage-gated calcium (Ca^{2+}) channels to open.
Step 2: Calcium ions (Ca^{2+}) enter the presynaptic neuron due to the concentration gradient. This influx of Ca^{2+} triggers the release of neurotransmitters stored in vesicles within the presynaptic neuron.
Step 3: The neurotransmitters are released into the synaptic cleft (the space between the presynaptic and postsynaptic neurons) via exocytosis. These neurotransmitters then diffuse across the synaptic cleft.
Step 4: The neurotransmitters bind to specific receptors on the postsynaptic neuron. This binding initiates a postsynaptic potential, which can either be excitatory or inhibitory, depending on the type of neurotransmitter and receptor involved.