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Multiple Choice
How does cholesterol affect the fluidity of biological membranes?
A
Cholesterol always decreases membrane fluidity regardless of temperature.
B
Cholesterol increases membrane fluidity at low temperatures and decreases it at high temperatures.
C
Cholesterol has no effect on membrane fluidity.
D
Cholesterol always increases membrane fluidity regardless of temperature.
Verified step by step guidance
1
Understand the structure of biological membranes: Biological membranes are primarily composed of a phospholipid bilayer, which includes hydrophilic heads and hydrophobic tails. Cholesterol is embedded within this bilayer and interacts with the phospholipids.
Recognize the role of cholesterol in membrane fluidity: Cholesterol acts as a regulator of fluidity by interacting with the fatty acid tails of phospholipids, preventing them from packing too closely or moving too freely.
Analyze the effect of cholesterol at low temperatures: At low temperatures, phospholipids tend to pack tightly, which decreases membrane fluidity. Cholesterol disrupts this tight packing, increasing fluidity and preventing the membrane from becoming too rigid.
Analyze the effect of cholesterol at high temperatures: At high temperatures, phospholipids move more freely, which increases membrane fluidity. Cholesterol restricts this excessive movement, decreasing fluidity and preventing the membrane from becoming too permeable.
Conclude the dual role of cholesterol: Cholesterol increases membrane fluidity at low temperatures and decreases it at high temperatures, maintaining an optimal balance for membrane function across varying conditions.