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Multiple Choice
Which enzyme is responsible for relaxing the supercoils in the DNA helix during replication?
A
Ligase
B
Helicase
C
Polymerase
D
Topoisomerase
Verified step by step guidance
1
Understand the problem: The question is asking about the enzyme that relaxes supercoils in the DNA helix during replication.
Recall the role of each enzyme listed: Ligase joins Okazaki fragments, Helicase unwinds the DNA double helix, Polymerase synthesizes new DNA strands, and Topoisomerase relieves the tension caused by supercoiling.
Focus on the function of Topoisomerase: This enzyme works by cutting the DNA strand, allowing it to unwind, and then rejoining it, which helps in relaxing the supercoils.
Consider the process of DNA replication: As the DNA helix unwinds, supercoiling occurs ahead of the replication fork, and Topoisomerase is crucial in managing this tension.
Conclude that Topoisomerase is the enzyme responsible for relaxing supercoils during DNA replication, ensuring the DNA can be properly replicated without damage or errors.