Multiple Choice
Which enzyme is responsible for relaxing the supercoils in the DNA helix during replication?
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7. Energy and Metabolism
Enzymes
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The induced fit model of enzyme activity suggests which of the following?
A
The enzyme changes shape to better fit the substrate upon binding.
B
The substrate changes shape to fit the enzyme's active site.
C
The enzyme is permanently altered after the reaction.
D
The enzyme and substrate fit together perfectly without any change in shape.
Verified step by step guidance1
Understand the concept of the induced fit model: This model suggests that enzymes are flexible and can change their shape to accommodate the substrate when it binds to the active site.
Recognize that the induced fit model contrasts with the lock-and-key model, where the enzyme and substrate fit together without any change in shape.
Identify that in the induced fit model, the enzyme undergoes a conformational change to better fit the substrate, enhancing the catalytic activity.
Note that the substrate does not change shape to fit the enzyme; rather, it is the enzyme that adjusts its shape.
Remember that the enzyme is not permanently altered after the reaction; it returns to its original shape once the product is released, ready to catalyze another reaction.
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