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Multiple Choice
Which of the following statements about translational initiation in bacteria is true?
A
The large ribosomal subunit binds before the small subunit during initiation.
B
The Shine-Dalgarno sequence helps position the ribosome correctly on the mRNA.
C
The small ribosomal subunit binds directly to the start codon.
D
Initiation factors are not required for the initiation process.
Verified step by step guidance
1
Understand the process of translational initiation in bacteria, which involves the assembly of the ribosome on the mRNA to begin protein synthesis.
Learn about the Shine-Dalgarno sequence, a purine-rich region on the mRNA that is complementary to a sequence on the 16S rRNA of the small ribosomal subunit. This sequence helps align the ribosome with the start codon.
Recognize that the small ribosomal subunit binds to the mRNA first, guided by the Shine-Dalgarno sequence, before the large subunit joins to form the complete ribosome.
Identify the role of initiation factors, which are proteins that assist in the assembly of the ribosome and the initiation of translation. These factors are crucial for the correct positioning and binding of the ribosomal subunits.
Evaluate the given statements based on your understanding of the bacterial translational initiation process, focusing on the role of the Shine-Dalgarno sequence and the order of ribosomal subunit binding.