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Multiple Choice
Which chromosomal change leads to Robertsonian translocation?
A
Fusion of two acrocentric chromosomes
B
Deletion of a chromosome segment
C
Duplication of a chromosome segment
D
Inversion of a chromosome segment
Verified step by step guidance
1
Understand the concept of Robertsonian translocation: It is a type of chromosomal rearrangement involving the fusion of two acrocentric chromosomes at their centromeres.
Identify acrocentric chromosomes: These are chromosomes with the centromere located near one end, resulting in one very short arm and one long arm.
Recognize the process of fusion: In Robertsonian translocation, the short arms of two acrocentric chromosomes are lost, and the long arms are fused together, forming a single chromosome.
Differentiate from other chromosomal changes: Compare Robertsonian translocation with other changes such as deletion, duplication, and inversion, which involve different mechanisms and outcomes.
Apply this understanding to the problem: The correct chromosomal change leading to Robertsonian translocation is the fusion of two acrocentric chromosomes.