Multiple Choice
Point mutations primarily alter which component of gene expression?
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15. Gene Expression
Mutations
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Which of the following mutations is most likely to cause a phenotypic change?
A
Neutral mutation
B
Nonsense mutation
C
Synonymous mutation
D
Silent mutation
Verified step by step guidance1
Understand the types of mutations: Neutral, Nonsense, Synonymous, and Silent mutations, and how they affect protein synthesis.
A Neutral mutation does not affect the organism's fitness and often occurs in non-coding regions of DNA.
A Nonsense mutation introduces a premature stop codon in the mRNA sequence, potentially leading to a truncated and nonfunctional protein.
A Synonymous mutation changes a codon to another codon that codes for the same amino acid, usually having no effect on the protein.
A Silent mutation also results in a codon that codes for the same amino acid, thus not affecting the protein's function. Therefore, a Nonsense mutation is most likely to cause a phenotypic change due to its impact on protein structure.
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