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Multiple Choice
Which of the following is required to replicate the lagging strand of DNA?
A
DNA helicase
B
Okazaki fragments
C
Single-strand binding proteins
D
Continuous synthesis
Verified step by step guidance
1
Understand that DNA replication involves the synthesis of a new strand of DNA complementary to the template strand. The lagging strand is synthesized discontinuously in short segments called Okazaki fragments.
Recognize that DNA helicase is an enzyme that unwinds the DNA double helix, creating two single strands that can be used as templates for replication.
Identify that single-strand binding proteins stabilize the unwound DNA strands, preventing them from re-annealing or forming secondary structures.
Acknowledge that continuous synthesis refers to the leading strand, which is synthesized in a continuous manner, unlike the lagging strand.
Conclude that Okazaki fragments are required for the replication of the lagging strand, as they are the short DNA segments synthesized discontinuously and later joined together by DNA ligase.