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Multiple Choice
During which phase of mitosis do the sister chromatids move to opposite sides of the cell?
A
Anaphase
B
Telophase
C
Metaphase
D
Prophase
Verified step by step guidance
1
Understand the process of mitosis, which is the division of a single cell into two genetically identical daughter cells. Mitosis consists of several phases: prophase, metaphase, anaphase, and telophase.
Recall that during prophase, the chromatin condenses into visible chromosomes, and the mitotic spindle begins to form. The nuclear envelope breaks down, but the sister chromatids are not yet separated.
In metaphase, the chromosomes align at the cell's equatorial plane, known as the metaphase plate. The sister chromatids are attached to spindle fibers from opposite poles, but they remain together at this stage.
During anaphase, the centromeres split, and the sister chromatids are pulled apart by the spindle fibers toward opposite poles of the cell. This is the phase where the sister chromatids move to opposite sides of the cell.
In telophase, the separated chromatids reach the opposite poles, and the nuclear envelope re-forms around each set of chromosomes, which begin to de-condense back into chromatin. This phase follows the separation of sister chromatids.