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Multiple Choice
Translation is terminated when a stop codon is presented at the ________ site.
A
A
B
A
C
P
D
E
Verified step by step guidance
1
Understand the process of translation: Translation is the process by which ribosomes synthesize proteins using mRNA as a template. It involves three main stages: initiation, elongation, and termination.
Learn about the ribosome binding sites: Ribosomes have three binding sites for tRNA molecules—A (aminoacyl), P (peptidyl), and E (exit). Each site plays a specific role during translation.
Focus on termination: Termination occurs when a stop codon (UAA, UAG, or UGA) is encountered in the mRNA sequence. Stop codons do not code for any amino acid and signal the ribosome to stop translation.
Determine the role of the A site: During termination, the stop codon is presented at the A site of the ribosome. This triggers the recruitment of release factors, which help disassemble the ribosome and release the newly synthesized polypeptide.
Conclude the process: Once the stop codon is recognized at the A site, the ribosome machinery halts, and the protein synthesis process is completed.