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Ch. 8 The Cellular Basis of Reproduction and Inheritance
Taylor - Campbell Biology: Concepts & Connections 10th Edition
Taylor, Simon, Dickey, Hogan10th EditionCampbell Biology: Concepts & ConnectionsISBN: 9780136538783Not the one you use?Change textbook
Chapter 8, Problem 6

If a fragment of a chromosome breaks off and then reattaches to the original chromosome but in the reverse direction, the resulting chromosomal abnormality is called
a. A deletion
b. An inversion
c. A translocation
d. A non-disjunction

Verified step by step guidance
1
Understand the problem: The question is asking about a specific type of chromosomal abnormality that occurs when a fragment of a chromosome breaks off and reattaches in the reverse direction. This requires knowledge of different types of chromosomal mutations.
Review the definitions of the options provided: a deletion refers to the loss of a chromosome segment, an inversion involves the reversal of a chromosome segment, a translocation refers to the transfer of a chromosome segment to a non-homologous chromosome, and nondisjunction is the failure of chromosomes to separate properly during cell division.
Focus on the key detail in the problem: The fragment reattaches to the original chromosome but in the reverse direction. This is a defining characteristic of an inversion.
Compare the description in the problem to the definitions of the options: The reversal of the chromosome segment matches the definition of an inversion, not deletion, translocation, or nondisjunction.
Conclude that the correct answer is the option that corresponds to the reversal of a chromosome segment, which is b. an inversion.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Chromosomal Inversion

A chromosomal inversion occurs when a segment of a chromosome breaks off, flips around, and reattaches in the reverse orientation. This alteration can affect gene expression and function, potentially leading to genetic disorders or variations. Inversions can be classified as paracentric (not including the centromere) or pericentric (including the centromere), influencing the genetic material's arrangement.
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Chromosomal Deletion

A chromosomal deletion is a type of mutation where a segment of the chromosome is lost or removed. This can result in the loss of essential genes, leading to various genetic disorders or developmental issues. Deletions can vary in size and may affect one or multiple genes, impacting the organism's phenotype significantly.
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Chromosomal Translocation

Chromosomal translocation occurs when a segment of one chromosome breaks off and attaches to another chromosome. This can lead to gene fusion or disruption, potentially causing cancer or genetic disorders. Translocations can be reciprocal, where two chromosomes exchange segments, or non-reciprocal, where a segment moves without an exchange.
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Related Practice
Textbook Question

Which of the following is not a function of mitosis in humans?

a. Repair of wounds

b. Growth

c. Production of gametes from diploid cells

d. Replacement of lost or damaged cells

2460
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Textbook Question

It is difficult to observe individual chromosomes during interphase because

a. The DNA has not been replicated yet

b. They are in the form of long, thin strands

c. They leave the nucleus and are dispersed to other parts of the cell

d. Homologous chromosomes do not pair up until division starts

2232
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Textbook Question

A fruit fly somatic cell contains 8 chromosomes. This means that ___________ different combinations of chromosomes are possible in its gametes.

a. 8

b. 16

c. 32

d. 64

3538
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Textbook Question

Which of the following phases of mitosis is essentially the opposite of prophase in terms of changes within the nucleus?

a. Telophase

b. Metaphase

c. Interphase

d. Anaphase

1871
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Textbook Question

A biochemist measured the amount of DNA in cells growing in the laboratory and found that the quantity of DNA in a cell doubled

a. Between prophase and anaphase of mitosis

b. Between the G1 and G2 phases of the cell cycle

c. During the M phase of the cell cycle

d. Between prophase I and prophase II of meiosis

1791
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Textbook Question

A micrograph of a dividing cell from a mouse showed 19 chromosomes, each consisting of two sister chromatids. During which of the following stages of cell division could such a picture have been taken? (Explain your answer.)

a. Prophase of mitosis

b. Telophase II of meiosis

c. Prophase I of meiosis

d. Prophase II of meiosis

1517
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