Multiple Choice
What does a mechanically gated channel respond to?
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14. Cell Signaling
Overview of Cell Surface Receptors
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How is the structure of kinesin related to its function in the cell?
A
Kinesin acts as a receptor tyrosine kinase, phosphorylating target proteins upon ligand binding.
B
Kinesin is a transmembrane protein that binds extracellular ligands to initiate signal transduction.
C
Kinesin forms ion channels that allow selective passage of ions across the plasma membrane.
D
Kinesin has two motor domains that bind to microtubules and hydrolyze ATP, enabling it to 'walk' along microtubules and transport cellular cargo.
Verified step by step guidance1
Understand the role of kinesin in the cell: Kinesin is a motor protein that facilitates intracellular transport by moving along microtubules, which are part of the cytoskeleton.
Examine the structure of kinesin: Kinesin has two motor domains (heads) that interact with microtubules and hydrolyze ATP to generate energy for movement.
Relate the motor domains to function: The motor domains bind to microtubules in a coordinated manner, allowing kinesin to 'walk' along the microtubule in a stepwise fashion.
Consider the energy source: ATP hydrolysis provides the energy required for the conformational changes in the motor domains, enabling the movement of kinesin and its cargo.
Connect the structure to cargo transport: Kinesin's tail region binds to specific cargo, such as vesicles or organelles, ensuring targeted delivery within the cell.
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