Table of contents

1. Overview of Cell Biology2h 49m
2. Chemical Components of Cells1h 14m
3. Energy1h 33m
4. DNA, Chromosomes, and Genomes2h 31m
5. DNA to RNA to Protein2h 31m
6. Proteins1h 36m
7. Gene Expression1h 42m
8. Membrane Structure1h 4m
- The Lipid Bilayer
  38m
- Membrane Proteins
  25m
9. Transport Across Membranes1h 52m
10. Anerobic Respiration1h 5m
11. Aerobic Respiration1h 11m
12. Photosynthesis52m
13. Intracellular Protein Transport2h 18m
14. Cell Signaling1h 28m
15. Cytoskeleton and Cell Movement1h 39m
16. Cell Division3h 5m
17. Meiosis and Sexual Reproduction50m
18. Cell Junctions and Tissues48m
19. Stem Cells13m
- Stem Cells
  13m
20. Cancer44m
21. The Immune System1h 6m
22. Techniques in Cell Biology1h 41m

14. Cell Signaling

Overview of Cell Surface Receptors

Cell Biology

14. Cell Signaling

Overview of Cell Surface Receptors

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Multiple Choice

Which of the following statements about SNARE-mediated membrane fusion is correct?

SNARE-mediated fusion requires direct energy input from ATP hydrolysis.

SNARE proteins facilitate membrane fusion by forming a tight complex that brings two membranes into close proximity.

SNARE proteins are only found in the plasma membrane and not in intracellular organelles.

SNARE-mediated fusion occurs independently of any regulatory proteins.

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Verified step by step guidance

Understand the role of SNARE proteins in membrane fusion: SNARE proteins are a family of proteins that mediate the fusion of vesicles with target membranes, a critical process in intracellular transport and secretion.

Clarify the mechanism of SNARE-mediated fusion: SNARE proteins on the vesicle (v-SNAREs) and target membrane (t-SNAREs) interact to form a tight, coiled complex. This interaction pulls the two membranes into close proximity, overcoming the energy barrier for membrane fusion.

Address the energy requirement: SNARE-mediated fusion does not directly require ATP hydrolysis for the fusion process itself. Instead, the energy for membrane fusion is derived from the formation of the SNARE complex. However, ATP hydrolysis may be involved in resetting or recycling SNARE proteins after fusion.

Consider the localization of SNARE proteins: SNARE proteins are not restricted to the plasma membrane. They are found in various intracellular organelles, facilitating vesicle trafficking throughout the cell.

Evaluate the role of regulatory proteins: SNARE-mediated fusion often involves regulatory proteins, such as Rab GTPases and tethering factors, which ensure specificity and proper timing of the fusion process. Thus, SNARE-mediated fusion does not occur entirely independently of regulatory proteins.