Multiple Choice
Apoptosis can only be stimulated through intracellular signals.
297
views
16. Cell Division
Control of Cell Death
Multiple Choice
In the context of control of cell death, cell death caused by poor blood flow (ischemia) is most accurately called which of the following?
A
Necrosis (typically ischemic/coagulative necrosis in solid tissues)
B
Anoikis (apoptosis triggered by loss of attachment to the extracellular matrix)
C
Autophagic cell death (cell death primarily associated with excessive autophagy)
D
Apoptosis (programmed cell death driven by caspases)
Verified step by step guidance1
Step 1: Understand the context of cell death types and their triggers. Cell death can occur through various mechanisms, including apoptosis, necrosis, autophagic cell death, and anoikis, each with distinct causes and characteristics.
Step 2: Define ischemia and its effect on cells. Ischemia refers to poor blood flow, which leads to a lack of oxygen and nutrients, causing cellular injury and death primarily due to energy failure and loss of membrane integrity.
Step 3: Identify the type of cell death caused by ischemia. Since ischemia results in uncontrolled cell damage and inflammation, the cell death is typically necrosis, characterized by cell swelling, membrane rupture, and release of cellular contents.
Step 4: Differentiate necrosis from other forms of cell death. Apoptosis is a programmed, caspase-driven process without inflammation; anoikis is apoptosis due to loss of extracellular matrix attachment; autophagic cell death involves excessive self-digestion. None of these match the uncontrolled damage seen in ischemia.
Step 5: Conclude that ischemic cell death is best described as necrosis, specifically coagulative necrosis in solid tissues, which is the hallmark of ischemic injury.
Related Videos
Related Practice
