Multiple Choice
Apoptosis can only be stimulated through intracellular signals.
297
views
16. Cell Division
Control of Cell Death
Multiple Choice
In the context of control of cell death, which of the following is NOT a typical cause of cell necrosis?
A
Toxin-induced disruption of plasma membrane integrity
B
ATP depletion due to ischemia (loss of blood supply)
C
Exposure to physical injury such as extreme heat or freezing
D
Activation of caspases during an orderly apoptotic program
Verified step by step guidance1
Step 1: Understand the difference between necrosis and apoptosis. Necrosis is a form of uncontrolled cell death often caused by external injury or stress, leading to cell swelling and rupture. Apoptosis is a programmed, orderly process involving caspase activation that leads to controlled cell dismantling without inflammation.
Step 2: Identify typical causes of necrosis. These include toxin-induced damage to the plasma membrane, ATP depletion due to ischemia, and physical injuries like extreme heat or freezing, all of which cause uncontrolled cell damage.
Step 3: Recognize that activation of caspases is a hallmark of apoptosis, not necrosis. Caspases are proteases that orchestrate the apoptotic program, leading to cell shrinkage and DNA fragmentation without membrane rupture.
Step 4: Compare the options given and note that toxin-induced membrane disruption, ATP depletion, and physical injury are all typical necrosis causes, whereas caspase activation is associated with apoptosis.
Step 5: Conclude that the option involving caspase activation during apoptosis is NOT a typical cause of necrosis, distinguishing it from the other necrosis-inducing factors.
Related Videos
Related Practice
