Table of contents

1. Overview of Cell Biology2h 49m
2. Chemical Components of Cells1h 14m
3. Energy1h 33m
4. DNA, Chromosomes, and Genomes2h 31m
5. DNA to RNA to Protein2h 31m
6. Proteins1h 36m
7. Gene Expression1h 42m
8. Membrane Structure1h 4m
- The Lipid Bilayer
  38m
- Membrane Proteins
  25m
9. Transport Across Membranes1h 52m
10. Anerobic Respiration1h 5m
11. Aerobic Respiration1h 11m
12. Photosynthesis52m
13. Intracellular Protein Transport2h 18m
14. Cell Signaling1h 28m
15. Cytoskeleton and Cell Movement1h 39m
16. Cell Division3h 5m
17. Meiosis and Sexual Reproduction50m
18. Cell Junctions and Tissues48m
19. Stem Cells13m
- Stem Cells
  13m
20. Cancer44m
21. The Immune System1h 6m
22. Techniques in Cell Biology1h 41m

14. Cell Signaling

Overview of Cell Surface Receptors

Cell Biology

14. Cell Signaling

Overview of Cell Surface Receptors

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Multiple Choice

Which of the following best describes the ligand that activates a G-protein linked receptor?

A phosphate group that attaches to the intracellular domain

A signaling molecule that binds to the extracellular domain of the receptor

A lipid molecule that integrates into the plasma membrane

A DNA fragment that enters the nucleus

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Verified step by step guidance

Understand the role of a G-protein linked receptor: These receptors are transmembrane proteins that transmit signals from the extracellular environment to the intracellular environment when activated by a ligand.

Identify the key feature of a ligand: A ligand is a signaling molecule that specifically binds to a receptor to initiate a cellular response. For G-protein linked receptors, this binding typically occurs on the extracellular domain.

Eliminate incorrect options: A phosphate group attaching to the intracellular domain is not a ligand but part of intracellular signaling. A lipid molecule integrating into the plasma membrane does not describe a ligand. A DNA fragment entering the nucleus is unrelated to G-protein linked receptor activation.

Focus on the correct option: The correct description of the ligand is 'A signaling molecule that binds to the extracellular domain of the receptor,' as this binding activates the receptor and triggers downstream signaling pathways.

Conclude by linking the ligand to receptor activation: Once the ligand binds to the extracellular domain, the receptor undergoes a conformational change, activating the associated G-protein and initiating intracellular signaling cascades.