Multiple Choice
In the context of viruses, why does a virus need a host cell to replicate?
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1. Overview of Cell Biology
Viruses
Multiple Choice
In HIV/AIDS infection, which type of immune cell is primarily targeted and depleted by the virus?
A
CD4+ T helper lymphocytes
B
CD8+ cytotoxic T lymphocytes
C
B lymphocytes (plasma cell precursors)
D
Neutrophils
Verified step by step guidance1
Understand the role of each immune cell type listed: CD4+ T helper lymphocytes coordinate immune responses, CD8+ cytotoxic T lymphocytes kill infected cells, B lymphocytes produce antibodies, and neutrophils are involved in innate immunity and phagocytosis.
Recall that HIV specifically targets cells that express the CD4 receptor on their surface, which is a key molecule for viral entry.
Identify that CD4+ T helper lymphocytes express the CD4 receptor, making them the primary target for HIV infection.
Recognize that the depletion of CD4+ T helper cells leads to weakened immune coordination, which is characteristic of AIDS progression.
Conclude that among the options, CD4+ T helper lymphocytes are the immune cells primarily targeted and depleted by HIV.
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