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Multiple Choice
During mitosis, which structure is directly responsible for moving chromosomes by attaching to kinetochores and generating forces that separate sister chromatids?
A
Kinetochore microtubules of the mitotic spindle
B
Centrioles that pull chromosomes by themselves
C
Actin microfilaments of the contractile ring
D
Intermediate filaments of the nuclear lamina
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Verified step by step guidance
1
Understand the role of the mitotic spindle during mitosis: it is responsible for chromosome movement and segregation.
Identify the components of the mitotic spindle: mainly microtubules, which include kinetochore microtubules, polar microtubules, and astral microtubules.
Focus on kinetochore microtubules, which attach directly to the kinetochores on chromosomes. These microtubules generate forces that pull sister chromatids apart toward opposite poles.
Recognize that centrioles serve as organizing centers for microtubules but do not directly pull chromosomes themselves.
Note that actin microfilaments and intermediate filaments have different roles: actin is involved in cytokinesis (contractile ring), and intermediate filaments maintain nuclear structure, not chromosome movement.