Multiple Choice
During mitosis in animal cells, which organelle serves as the microtubule-organizing center that anchors the spindle fibers at each pole?
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15. Cytoskeleton and Cell Movement
Microtubules and Cell Division
Multiple Choice
In animal cells, the mitotic spindle arises primarily from which cell structure?
A
The rough endoplasmic reticulum, which anchors spindle microtubules to the nuclear envelope
B
The centrosomes (microtubule-organizing centers containing a pair of centrioles)
C
The Golgi apparatus, which nucleates microtubules for chromosome movement
D
The nucleolus, which polymerizes tubulin into spindle fibers during prophase
Verified step by step guidance1
Understand the role of the mitotic spindle in animal cells: it is responsible for separating chromosomes during cell division.
Recall that the mitotic spindle is composed of microtubules, which are polymers of tubulin proteins.
Identify the cellular structure that acts as the main microtubule-organizing center (MTOC) in animal cells; this structure nucleates and anchors microtubules to form the spindle.
Recognize that centrosomes, which contain a pair of centrioles, serve as the primary MTOCs in animal cells and are crucial for spindle formation.
Eliminate other options by understanding their functions: the rough endoplasmic reticulum is involved in protein synthesis, the Golgi apparatus processes and packages proteins, and the nucleolus is involved in ribosome production, none of which nucleate spindle microtubules.
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