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Multiple Choice
During which phase of the cell cycle is DNA replicated, resulting in duplicated chromosomes (sister chromatids) prior to mitosis?
A
Telophase
B
Prophase
C
Metaphase
D
S phase of interphase
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Verified step by step guidance
1
Understand the overall cell cycle, which consists of interphase and mitotic phase (M phase). Interphase includes G1, S, and G2 phases, where the cell prepares for division.
Identify that DNA replication occurs during the S phase (Synthesis phase) of interphase, where each chromosome is duplicated to form sister chromatids.
Recognize that mitosis follows interphase and includes phases such as prophase, metaphase, anaphase, and telophase, but DNA replication does not occur during these phases.
Recall that during prophase, chromosomes condense, during metaphase they align at the cell equator, and during telophase the cell prepares to divide, but the DNA has already been duplicated in the S phase.
Conclude that the correct phase for DNA replication and formation of sister chromatids is the S phase of interphase, prior to mitosis.