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Multiple Choice
In the eukaryotic cell cycle, when are chromosomes duplicated relative to mitosis?
A
During anaphase of mitosis, when sister chromatids separate
B
During prophase of mitosis, as chromosomes condense
C
During metaphase of mitosis, when chromosomes align at the metaphase plate
D
During S phase of interphase, before mitosis begins
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Verified step by step guidance
1
Understand the phases of the eukaryotic cell cycle: G1 phase (cell growth), S phase (DNA synthesis), G2 phase (preparation for mitosis), and M phase (mitosis).
Recall that chromosome duplication refers to the replication of DNA, which occurs during the S phase of interphase, not during mitosis itself.
Recognize that mitosis is the process where duplicated chromosomes are separated into two daughter cells, starting with prophase and ending with telophase.
Note that during prophase, chromosomes condense but are already duplicated; during metaphase, chromosomes align at the metaphase plate; and during anaphase, sister chromatids separate.
Conclude that chromosomes are duplicated during the S phase of interphase, which occurs before mitosis begins.