Multiple Choice
Which of the following is not a type of DNA damage repair?
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16. Cell Division
DNA Repair and Recombination
Multiple Choice
In the context of DNA repair and recombination, which cellular component is most directly damaged by UV radiation, leading to lesions such as pyrimidine (thymine) dimers?
A
Microtubules of the mitotic spindle
B
Ribosomal RNA in the nucleolus
C
The phospholipid bilayer of the plasma membrane
D
Nuclear DNA
Verified step by step guidance1
Understand that UV radiation primarily affects molecules that absorb UV light strongly, such as nucleic acids and proteins.
Recall that UV radiation causes specific types of DNA damage, notably the formation of covalent bonds between adjacent pyrimidine bases, especially thymine, resulting in thymine dimers.
Recognize that these thymine dimers distort the DNA double helix, interfering with replication and transcription processes.
Identify that the cellular component directly damaged by UV radiation in this context is the nuclear DNA, where these lesions occur.
Note that other cellular components listed, such as microtubules, ribosomal RNA, and the plasma membrane, are not the primary targets for UV-induced pyrimidine dimer formation.
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