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Multiple Choice
In the context of the eukaryotic cell cycle, what must occur before mitosis (M phase) can begin?
A
DNA must be replicated during S phase so each daughter cell can receive a complete genome.
B
The nuclear envelope must permanently disassemble so chromosomes remain in the cytoplasm after division.
C
Sister chromatids must separate at the centromere to form two nuclei before mitosis starts.
D
Cytokinesis must occur to divide the cytoplasm into two daughter cells prior to mitosis.
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Verified step by step guidance
1
Understand the phases of the eukaryotic cell cycle: G1 (gap 1), S (synthesis), G2 (gap 2), and M (mitosis). Each phase has specific events that prepare the cell for division.
Recognize that before mitosis (M phase) begins, the cell must have duplicated its DNA to ensure that each daughter cell receives a complete set of chromosomes. This duplication occurs during the S phase.
Note that the nuclear envelope does not permanently disassemble before mitosis; instead, it temporarily breaks down during mitosis to allow chromosome segregation and then re-forms afterward.
Understand that sister chromatids separate at the centromere during mitosis (specifically in anaphase), not before mitosis starts.
Know that cytokinesis, the division of the cytoplasm, occurs after mitosis is complete, not before it begins.