Multiple Choice
In an overview of the eukaryotic cell cycle, which of the following is NOT considered a standard phase of the cell cycle?
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16. Cell Division
Overview of the Cell Cycle
Multiple Choice
Which type of cell does NOT undergo mitosis as part of its normal life cycle?
A
Intestinal crypt stem cells
B
Hepatocytes during liver regeneration
C
Mature mammalian red blood cells (erythrocytes)
D
Basal cells of the epidermis
Verified step by step guidance1
Understand the process of mitosis: Mitosis is a type of cell division that results in two daughter cells each having the same number and kind of chromosomes as the parent nucleus, typical of ordinary tissue growth.
Identify the cell types listed and their typical behavior regarding mitosis: Intestinal crypt stem cells, hepatocytes during liver regeneration, and basal cells of the epidermis are all known to divide by mitosis as part of normal tissue maintenance or repair.
Recall the characteristics of mature mammalian red blood cells (erythrocytes): These cells lose their nucleus during maturation and therefore cannot undergo mitosis because mitosis requires a nucleus to replicate DNA and divide.
Conclude that mature mammalian red blood cells do not undergo mitosis as part of their normal life cycle due to the absence of a nucleus, unlike the other cell types listed which retain their nuclei and proliferate through mitosis.
Summarize that the key factor preventing mitosis in mature erythrocytes is the loss of the nucleus, which is essential for the mitotic process.
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