In eukaryotic DNA, where are you most likely to find histone protein H4?
Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
7. DNA and Chromosome Structure
Eukaryotic Chromosome Structure
Problem 6
Textbook Question
During what genetic process are lampbrush chromosomes present in vertebrates?

1
Understand that lampbrush chromosomes are a specialized form of chromosomes found in certain vertebrates during a specific stage of cell division.
Recall that lampbrush chromosomes are highly extended and transcriptionally active, allowing for the synthesis of RNA. This structure is associated with the need for high levels of gene expression.
Identify that lampbrush chromosomes are typically observed during the diplotene stage of meiosis I in oocytes (egg cells) of vertebrates.
Recognize that the extended loops of lampbrush chromosomes are sites of active transcription, which is crucial for the development of the oocyte and preparation for fertilization.
Conclude that lampbrush chromosomes are present during meiosis, specifically in the diplotene stage, and their function is tied to the transcriptional activity required for oocyte maturation.

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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Lampbrush Chromosomes
Lampbrush chromosomes are specialized structures found in the oocytes of many vertebrates during the diplotene stage of prophase I of meiosis. They are characterized by their large size and extensive loops of chromatin, which are sites of active transcription. These chromosomes facilitate the synthesis of RNA and proteins necessary for oocyte development.
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Meiosis
Meiosis is a type of cell division that reduces the chromosome number by half, resulting in the formation of gametes (sperm and eggs). It consists of two sequential divisions: meiosis I and meiosis II. During meiosis I, homologous chromosomes are separated, while meiosis II resembles mitosis, separating sister chromatids. This process is crucial for sexual reproduction and genetic diversity.
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Meiosis Overview
Prophase I
Prophase I is the first stage of meiosis, where homologous chromosomes pair up and exchange genetic material through a process called crossing over. This stage is divided into several sub-stages, including leptotene, zygotene, pachytene, diplotene, and diakinesis. The presence of lampbrush chromosomes is specifically noted during the diplotene stage, highlighting the preparatory activities for gamete formation.
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