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Multiple Choice
Which of the following best explains why many mutations may be deleterious?
A
They result in the duplication of entire chromosomes, which is always advantageous.
B
They always increase the rate of beneficial traits in a population.
C
They only occur in non-coding regions and have no effect on gene expression.
D
They can alter the amino acid sequence of proteins, potentially disrupting their normal function.
Verified step by step guidance
1
Understand what a mutation is: a change in the DNA sequence that can affect how genes are expressed or how proteins are made.
Recognize that proteins are made up of amino acids, and their function depends on the specific sequence of these amino acids.
Know that mutations can change the DNA sequence in a way that alters the amino acid sequence of a protein, which may disrupt the protein's normal structure and function.
Realize that when protein function is disrupted, it can negatively affect the organism, making the mutation deleterious (harmful).
Conclude that this explains why many mutations are deleterious: because they can alter proteins in ways that impair their normal roles in the cell.