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Multiple Choice
Which of the following statements best describes proto-oncogenes?
A
They are genes that directly suppress tumor formation.
B
They are viral genes that cause cancer in host cells.
C
They are normal genes that can become oncogenes when mutated.
D
They are genes that repair damaged DNA in the cell cycle.
Verified step by step guidance
1
Understand the definition of proto-oncogenes: Proto-oncogenes are normal genes that play a role in regulating cell growth and division.
Recognize that when proto-oncogenes undergo mutations or are abnormally activated, they can become oncogenes, which have the potential to cause uncontrolled cell proliferation leading to cancer.
Differentiate proto-oncogenes from tumor suppressor genes, which are genes that normally act to prevent tumor formation by inhibiting cell division or promoting apoptosis.
Note that viral genes causing cancer are called viral oncogenes, which are distinct from proto-oncogenes that exist naturally in the host genome.
Understand that genes involved in DNA repair are separate from proto-oncogenes; their role is to maintain genome integrity rather than directly promoting cell growth.