Table of contents

1. Introduction to Genetics51m
2. Mendel's Laws of Inheritance3h 37m
3. Extensions to Mendelian Inheritance2h 41m
4. Genetic Mapping and Linkage2h 28m
5. Genetics of Bacteria and Viruses1h 21m
6. Chromosomal Variation1h 48m
7. DNA and Chromosome Structure56m
8. DNA Replication1h 10m
9. Mitosis and Meiosis1h 34m
10. Transcription1h 0m
11. Translation58m
12. Gene Regulation in Prokaryotes1h 19m
13. Gene Regulation in Eukaryotes44m
14. Genetic Control of Development44m
15. Genomes and Genomics1h 50m
16. Transposable Elements47m
17. Mutation, Repair, and Recombination1h 6m
18. Molecular Genetic Tools19m
- Genetic Cloning
  9m
- Methods for Analyzing DNA
  9m
19. Cancer Genetics29m
- Overview of Cancer
  21m
- Cancer Mutations
  7m
20. Quantitative Genetics1h 26m
21. Population Genetics50m
- Hardy Weinberg
  19m
- Allelic Frequency Changes
  31m
22. Evolutionary Genetics29m

3. Extensions to Mendelian Inheritance

Overview of interacting Genes

Genetics

3. Extensions to Mendelian Inheritance

Overview of interacting Genes

Previous problemNext problem

Struggling with Genetics?

Join thousands of students who trust us to help them ace their exams!Watch the first video

Multiple Choice

If DNA rearrangement occurs within the α-chain locus of immunoglobulin genes, which of the following is most likely to result?

Production of non-functional ribosomal RNA

Increased mutation rate in mitochondrial DNA

Diversity in the antigen-binding sites of antibodies

Inactivation of the β-chain gene

Previous problemNext problem

Verified step by step guidance

Understand that the α-chain locus refers to the gene segments encoding the alpha chain of immunoglobulins (antibodies).

Recall that DNA rearrangement in immunoglobulin genes is a process called V(D)J recombination, which shuffles variable (V), diversity (D), and joining (J) gene segments to create diverse antigen-binding sites.

Recognize that this rearrangement specifically increases the diversity of antibodies by producing different variable regions in the α-chain, allowing the immune system to recognize a wide variety of antigens.

Note that this process does not affect ribosomal RNA production, mitochondrial DNA mutation rates, or the β-chain gene directly, as these are unrelated to the α-chain locus rearrangement.

Conclude that the most likely result of DNA rearrangement within the α-chain locus is increased diversity in the antigen-binding sites of antibodies.