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1. Introduction to Genetics51m
2. Mendel's Laws of Inheritance3h 37m
3. Extensions to Mendelian Inheritance2h 41m
4. Genetic Mapping and Linkage2h 28m
5. Genetics of Bacteria and Viruses1h 21m
6. Chromosomal Variation1h 48m
7. DNA and Chromosome Structure56m
8. DNA Replication1h 10m
9. Mitosis and Meiosis1h 34m
10. Transcription1h 0m
11. Translation58m
12. Gene Regulation in Prokaryotes1h 19m
13. Gene Regulation in Eukaryotes44m
14. Genetic Control of Development44m
15. Genomes and Genomics1h 50m
16. Transposable Elements47m
17. Mutation, Repair, and Recombination1h 6m
18. Molecular Genetic Tools19m
- Genetic Cloning
  9m
- Methods for Analyzing DNA
  9m
19. Cancer Genetics29m
- Overview of Cancer
  21m
- Cancer Mutations
  7m
20. Quantitative Genetics1h 26m
21. Population Genetics50m
- Hardy Weinberg
  19m
- Allelic Frequency Changes
  31m
22. Evolutionary Genetics29m

17. Mutation, Repair, and Recombination

DNA Repair

Genetics

17. Mutation, Repair, and Recombination

DNA Repair

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Multiple Choice

Proofreading of newly-synthesized DNA is important because:

it increases the rate of DNA replication

it allows for the removal of introns from pre-mRNA

it reduces the frequency of replication errors, ensuring genetic fidelity

it initiates the process of transcription

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Verified step by step guidance

Understand the role of proofreading in DNA replication: proofreading is a mechanism used by DNA polymerases to check and correct errors during DNA synthesis.

Recall that DNA replication must be highly accurate to maintain genetic information across generations, so any errors (mutations) need to be minimized.

Recognize that proofreading involves the DNA polymerase detecting mismatched bases and removing them through its 3' to 5' exonuclease activity before continuing replication.

Note that this process reduces the frequency of replication errors, thereby ensuring the fidelity of the genetic code passed on to daughter cells.

Differentiate proofreading from other processes such as intron removal (which occurs during RNA processing) and transcription initiation, which are unrelated to DNA replication accuracy.