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Multiple Choice
If complementary DNA strands were arranged in a parallel manner (rather than antiparallel), what would you expect to observe?
A
The DNA double helix would become more stable due to enhanced base pairing.
B
The genetic code would be read in the same direction on both strands.
C
DNA replication would proceed normally without any changes.
D
Hydrogen bonding between bases would be disrupted, preventing stable double helix formation.
Verified step by step guidance
1
Recall the normal structure of DNA, where two complementary strands run in opposite directions (antiparallel), one strand from 5' to 3' and the other from 3' to 5'.
Understand that base pairing (A-T and G-C) depends on the antiparallel orientation to allow proper hydrogen bonding between complementary bases.
Consider what happens if the strands are arranged parallel (both running 5' to 3' or both 3' to 5'): the alignment of bases would be altered, disrupting the hydrogen bonding pattern.
Recognize that without proper hydrogen bonding, the double helix cannot form a stable structure, leading to instability or failure to form the typical DNA double helix.
Conclude that the genetic code reading and replication processes rely on the stable double helix structure, so parallel strands would prevent normal DNA function.