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Multiple Choice
In the context of Mendelian genetics, how do two alleles for the same gene most commonly differ?
A
They are two separate traits controlled by the same gene through pleiotropy.
B
They are genes located on different chromosomes that control the same trait.
C
They are different versions of the same gene that typically differ in their DNA nucleotide sequence at a specific locus.
D
They are identical DNA sequences but are expressed in different tissues due to alternative splicing.
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Verified step by step guidance
1
Understand that alleles are different forms or versions of the same gene located at the same position (locus) on homologous chromosomes.
Recognize that these alleles differ primarily in their DNA nucleotide sequences, which can lead to variations in the gene product or its expression.
Note that alleles are not separate genes or traits, but variations of a single gene influencing a particular trait.
Distinguish this from concepts like pleiotropy (one gene affecting multiple traits) or genes on different chromosomes controlling the same trait, which are different genetic phenomena.
Conclude that the most common difference between two alleles is their DNA sequence variation at a specific locus, which can affect the phenotype.