Multiple Choice
During DNA replication, what is the primary function of primase?
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8. DNA Replication
Overview of DNA Replication
Multiple Choice
In the overview of DNA replication, which enzyme unwinds ("unzips") the parental DNA double helix at the replication fork?
A
Primase
B
DNA polymerase III
C
DNA helicase
D
DNA ligase
Verified step by step guidance1
Understand the role of each enzyme listed in the context of DNA replication.
Recall that the enzyme responsible for unwinding or "unzipping" the parental DNA double helix at the replication fork is the one that breaks the hydrogen bonds between complementary base pairs.
Identify that DNA helicase is the enzyme that performs this function by separating the two strands to allow replication to proceed.
Note that primase synthesizes RNA primers, DNA polymerase III synthesizes the new DNA strand, and DNA ligase joins Okazaki fragments on the lagging strand.
Conclude that DNA helicase is the enzyme that unwinds the DNA double helix at the replication fork.
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