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Multiple Choice
In gel electrophoresis, how does the rate of travel differ between small DNA fragments and large DNA fragments?
A
DNA fragment size does not affect the rate of travel in gel electrophoresis.
B
Large DNA fragments move faster through the gel than small DNA fragments.
C
Small DNA fragments move faster through the gel than large DNA fragments.
D
Both small and large DNA fragments move at the same rate through the gel.
Verified step by step guidance
1
Understand that gel electrophoresis separates DNA fragments based on their size by applying an electric field to a gel matrix.
Recognize that the gel acts like a molecular sieve, where smaller DNA fragments can navigate through the pores of the gel more easily than larger fragments.
Recall that the rate of travel of DNA fragments through the gel is inversely related to their size: smaller fragments move faster because they encounter less resistance.
Note that larger DNA fragments move more slowly because their size causes more friction and difficulty passing through the gel pores.
Conclude that in gel electrophoresis, small DNA fragments travel faster through the gel compared to large DNA fragments.