Multiple Choice
Which of the following best describes the function of DNA replication complexes during DNA synthesis?
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8. DNA Replication
Overview of DNA Replication
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Which DNA polymerase is primarily responsible for initiating DNA synthesis in prokaryotic cells during DNA replication?
A
DNA polymerase II
B
DNA polymerase III
C
RNA polymerase
D
DNA polymerase I
Verified step by step guidance1
Understand the role of different DNA polymerases in prokaryotic DNA replication. DNA polymerase I, II, and III have distinct functions during replication.
Recall that DNA polymerase III is the main enzyme responsible for the bulk of DNA synthesis during replication, adding nucleotides to the growing DNA strand.
Recognize that DNA polymerase I primarily functions to remove RNA primers and replace them with DNA nucleotides, rather than initiating synthesis.
Note that RNA polymerase synthesizes RNA primers but does not synthesize DNA; it is not a DNA polymerase.
Conclude that DNA polymerase III is the enzyme that initiates and carries out the majority of DNA strand elongation in prokaryotic cells.
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