Multiple Choice
During cell division, DNA coils tightly and assembles into visible structures known as:
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8. DNA Replication
Overview of DNA Replication
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Which enzyme joins nucleotides to synthesize a new complementary DNA strand during DNA replication?
A
DNA ligase
B
Primase
C
Helicase
D
DNA polymerase
Verified step by step guidance1
Understand the role of each enzyme listed in the problem: DNA ligase, Primase, Helicase, and DNA polymerase.
Recall that Helicase unwinds the DNA double helix by breaking hydrogen bonds between base pairs, preparing the strands for replication.
Recognize that Primase synthesizes a short RNA primer to provide a starting point for DNA synthesis.
Know that DNA polymerase is the enzyme responsible for adding nucleotides to the growing complementary DNA strand by matching bases to the template strand.
Note that DNA ligase functions later by joining Okazaki fragments on the lagging strand, but it does not synthesize the new strand itself.
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