What is meant by the term chromatin remodeling? Describe the i...

Question

What is meant by the term chromatin remodeling? Describe the importance of this process to transcription.

Accepted Answer

Hi, everyone. Welcome back. Here's our next problem. The process of changing the DNA structure to allow or prevent access to the genetic information as termed a chromatin condensation. B chromatin remodeling C chromatin amplification or D chromatin looping. When we think about a change to DNA structure that allows or prevents access to the genetic information, we'd be thinking about the fact that making the chromatin more tightly or loosely packed actually affects whether the enzymes that transcribe the genes can physically get in and perform transcription. So tightly packed chromatin or highly condensed chromatin means that transcription is reduced or even prevented because it actually is preventing access to the DNA template for transcription to take place. And then of course, vice versa. If the chromatin is loosely packed, transcription is loud as the enzymes can access the DNA template to carry out transcription and that can change back and forth. So it's not permanently condensed or permanently loosened. There are processes that take place that can actually change how loosely or tightly packed the chromatin is. And that process of changing the DNA structure. A form of gene gene regulation is choice B chromatin remodeling when we look at our other answer. Choices, choice, a chromatin condensation, that's a form of chromatin modeling, but only one of them because you could also have your chromatin loosening due to changes. So I see chromatin amplification um that may make us think of gene amplification where you get multiple copies of a gene uh happening but is not the process of changing chromatin that we're looking for. And then finally, choice D chromatin looping would refer to the actual looping of the chromatin around the his stones, which is not in itself changing the structure. That's just part of how the structure of chromatin is organized in that those loops of chromatin around the histone protein. So choice D is not our answer choice either. So again, the process of changing the DNA structure allowing or preventing access to the information. This choice be chromatin remodeling. See you in the next video.

What is meant by the term chromatin remodeling? Describe the importance of this process to transcription.

Key Concepts

Chromatin Structure

Chromatin Remodeling

Role of Chromatin Remodeling in Transcription

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