Table of contents

1. Introduction to Genetics51m
2. Mendel's Laws of Inheritance3h 37m
3. Extensions to Mendelian Inheritance2h 41m
4. Genetic Mapping and Linkage2h 28m
5. Genetics of Bacteria and Viruses1h 21m
6. Chromosomal Variation1h 48m
7. DNA and Chromosome Structure56m
8. DNA Replication1h 10m
9. Mitosis and Meiosis1h 34m
10. Transcription1h 0m
11. Translation58m
12. Gene Regulation in Prokaryotes1h 19m
13. Gene Regulation in Eukaryotes44m
14. Genetic Control of Development44m
15. Genomes and Genomics1h 50m
16. Transposable Elements47m
17. Mutation, Repair, and Recombination1h 6m
18. Molecular Genetic Tools19m
- Genetic Cloning
  9m
- Methods for Analyzing DNA
  9m
19. Cancer Genetics29m
- Overview of Cancer
  21m
- Cancer Mutations
  7m
20. Quantitative Genetics1h 26m
21. Population Genetics50m
- Hardy Weinberg
  19m
- Allelic Frequency Changes
  31m
22. Evolutionary Genetics29m

3. Extensions to Mendelian Inheritance

Overview of interacting Genes

Genetics

3. Extensions to Mendelian Inheritance

Overview of interacting Genes

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Multiple Choice

Which proteins form ionic interactions with the negatively charged phosphates of the DNA backbone?

Ligases

Helicases

Histones

DNA polymerases

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Verified step by step guidance

Understand the structure of DNA: DNA has a backbone made of sugar and phosphate groups. The phosphate groups carry a negative charge, which influences how proteins interact with DNA.

Recall the role of histones: Histones are positively charged proteins that bind to the negatively charged phosphate groups on the DNA backbone, helping to package and organize DNA into chromatin.

Consider the other proteins listed: Ligases are enzymes that join DNA strands, helicases unwind DNA strands, and DNA polymerases synthesize new DNA strands. None of these primarily interact with the phosphate backbone through ionic interactions.

Focus on the nature of ionic interactions: Since phosphate groups are negatively charged, proteins that form ionic bonds with them must have positively charged amino acid residues, which is characteristic of histones.

Conclude that histones are the proteins that form ionic interactions with the negatively charged phosphates of the DNA backbone, stabilizing the DNA structure within the nucleus.