Refer to Table 13.1. Can you hypothesize why a synthetic RNA composed of a mixture of poly U poly A would not stimulate incorporation of ¹⁴C-phenylalanine into protein?
Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
10. Transcription
Overview of Transcription
Problem 39g
Textbook Question
Answer the following questions about the accompanying diagram.

What structure is closest to E? Be specific.

1
Examine the diagram provided. The structure labeled 'E' is part of the transcription process, specifically the mRNA strand being synthesized.
Identify the structures surrounding 'E'. The closest structure to 'E' is labeled 'D', which represents a ribosome attached to the mRNA strand.
Understand the relationship between 'E' and 'D'. The ribosome (D) is responsible for translating the mRNA (E) into a polypeptide chain during translation.
Note the other structures in the diagram. 'F' and 'G' represent the growing polypeptide chains being synthesized by the ribosomes, while 'A' is the DNA template and 'B' is the RNA polymerase.
Conclude that the structure closest to 'E' is 'D', the ribosome, which is directly interacting with the mRNA strand during translation.

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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Transcription
Transcription is the process by which the genetic information encoded in DNA is copied into messenger RNA (mRNA). This process involves the enzyme RNA polymerase, which binds to the DNA at a specific region and synthesizes a complementary RNA strand. Understanding transcription is crucial for identifying the roles of various structures in the diagram, particularly in relation to structure E.
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RNA Polymerase
RNA polymerase is the enzyme responsible for synthesizing RNA from a DNA template during transcription. It unwinds the DNA double helix and adds RNA nucleotides in a sequence complementary to the DNA strand. In the diagram, structure E is likely associated with RNA polymerase, making it essential to recognize its function and location in the transcription process.
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Promoter Region
The promoter region is a specific sequence of DNA located upstream of a gene that signals the start of transcription. It is where RNA polymerase binds to initiate the transcription process. In the context of the diagram, understanding the promoter's role helps in identifying which structure is closest to E, as it is typically located near the transcription start site.
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