Multiple Choice
In the context of cancer mutations, what is a tumor suppressor gene?
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19. Cancer Genetics
Cancer Mutations
Multiple Choice
A mutation in a tumor suppressor gene causes what to happen?
A
The mutated tumor suppressor acts to suppress the tumor
B
The mutated tumor suppressor can no longer act to suppress the tumor, and allows tumor growth
C
The mutated tumor suppressor has no direct contribution to the cancer
Verified step by step guidance1
Understand the role of tumor suppressor genes: These genes are responsible for regulating cell growth and division, preventing cells from undergoing uncontrolled proliferation.
Recognize the impact of mutations: A mutation in a tumor suppressor gene can lead to a loss of function, meaning the gene can no longer effectively regulate cell growth.
Consider the consequences of a loss of function: Without the regulatory action of the tumor suppressor gene, cells may begin to grow and divide uncontrollably, potentially leading to tumor formation.
Differentiate between the options: The mutated tumor suppressor gene does not suppress the tumor; instead, it fails to prevent tumor growth due to its loss of function.
Conclude with the correct understanding: The mutation in the tumor suppressor gene allows for tumor growth because it can no longer perform its role in suppressing cell proliferation.
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